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AGPAT9 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q53EU6
Clone Names 90909010
Additional Information
Gene ID 84803
Other Names Glycerol-3-phosphate acyltransferase 3, GPAT-3, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10, AGPAT 10, 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9, 1-AGP acyltransferase 9, 1-AGPAT 9, Acyl-CoA:glycerol-3-phosphate acyltransferase 3, hGPAT3, Lung cancer metastasis-associated protein 1, Lysophosphatidic acid acyltransferase theta, LPAAT-theta, MAG-1, AGPAT9, GPAT3, MAG1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPAT3 (HGNC:28157)
Synonyms AGPAT9, MAG1
Function Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:17170135). Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:19318427). Protects cells against lipotoxicity (PubMed:30846318).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Expressed in liver, kidney, testis, brain, heart, skeletal muscle, thyroid, prostate, thymus and placenta. Also expressed lung and adipose tissue
Research Areas
Citations (0)
citation

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Background

Glycerol-3-phosphate (G3P) acyltransferases (GPAT; EC2.3.1.15), such as GPAM (MIM 602395) and GPAT3, catalyze theinitial step of de novo triacylglycerol (TAG) synthesis byconverting glycerol-3-phosphate (G3P) to lysophosphatidic acid(LPA) (Cao et al., 2006 [PubMed 17170135]).

References

Shan, D., et al. J. Lipid Res. 51(7):1971-1981(2010)Cao, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(52):19695-19700(2006)Tang, W., et al. J. Biochem. Mol. Biol. 39(5):626-635(2006)Yamada, S., et al. Oncogene 23(35):5901-5911(2004)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 277.78
Cat# BP18013c
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