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FIGLA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6QHK4
Clone Names 91119033
Peptide ID 91119033
Additional Information
Gene ID 344018
Other Names Factor in the germline alpha, FIGalpha, Class C basic helix-loop-helix protein 8, bHLHc8, Folliculogenesis-specific basic helix-loop-helix protein, Transcription factor FIGa, FIGLA, BHLHC8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BHLHC8
Function Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E- box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Cellular Location Nucleus.
Tissue Location Germ cells. Expressed in the fetal ovary, but not by a range of other tissues. Expression increases across mid- gestation, rising some 40-fold by the time of primordial follicle formation.
Research Areas
Citations (0)

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This gene encodes a protein that functions in postnataloocyte-specific gene expression. The protein is a basichelix-loop-helix transcription factor that regulates multipleoocyte-specific genes, including genes involved in folliculogenesisand those that encode the zona pellucida. Mutations in this genecause premature ovarian failure type 6.


van Dooren, M.F., et al. Curr. Opin. Obstet. Gynecol. 21(4):313-317(2009)Fowler, P.A., et al. J. Clin. Endocrinol. Metab. 94(4):1427-1435(2009)Tormala, R.M., et al. Mol. Cell. Endocrinol. 289 (1-2), 10-15 (2008) :Zhao, H., et al. Am. J. Hum. Genet. 82(6):1342-1348(2008)Suzumori, N., et al. Curr. Med. Chem. 14(3):353-357(2007)

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$ 80.00
Cat# BP18020c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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