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FCHO2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q0JRZ9
Clone Names 91102209
Peptide ID 91102209
Additional Information
Gene ID 115548
Other Names FCH domain only protein 2, FCHO2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCHO2
Function Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP- 2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
Cellular Location Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2 (By similarity).
Research Areas
Citations (0)

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FCHO2 may play a role in membrane remodeling by imposing and stabilizing particular membrane curvatures.


Henne, W.M., et al. Structure 15(7):839-852(2007)Katoh, M., et al. Int. J. Mol. Med. 14(2):327-331(2004)

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$ 80.00
Cat# BP18034c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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