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HHIP Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96QV1 |
|---|---|
| Clone Names | 100517111 |
| Gene ID | 64399 |
|---|---|
| Other Names | Hedgehog-interacting protein, HHIP, HIP, HHIP, HIP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HHIP |
|---|---|
| Synonyms | HIP |
| Function | Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. |
| Cellular Location | Cell membrane; Peripheral membrane protein. Secreted. Note=The last 22 C- terminal amino acids may participate in cell membrane attachment |
| Tissue Location | Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. {ECO:0000269|PubMed:11435703, ECO:0000269|Ref.1} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein similar to the mousehedgehog-interacting protein, a regulatory component of thehedgehog signalling pathway. Members of the hedgehog family areevolutionarily conserved proteins which are involved in manyfundamental processes in embryonic development, includinganteroposterior patterns of limbs and regulation of left-rightasymmetry.
References
Pillai, S.G., et al. Am. J. Respir. Crit. Care Med. (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Liu, J.Z., et al. Twin Res Hum Genet 13(2):179-193(2010)Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010)Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
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