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FNTA Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P49354
Clone Names 100617092
Peptide ID 100617092
Additional Information
Gene ID 2339
Other Names Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Research Areas
Citations (0)

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Prenyltransferases can attach either a farnesyl group or ageranylgeranyl group in thioether linkage to the cysteine residueof proteins with a C-terminal CAAX box. CAAXgeranylgeranyltransferase and CAAX farnesyltransferase areheterodimers that share the same alpha subunit but have differentbeta subunits. This gene encodes the alpha subunit of thesetransferases. Alternative splicing results in multiple transcriptvariants. Related pseudogenes have been identified on chromosomes11 and 13.


Lipkin, S.M., et al. Cancer Prev Res (Phila Pa) 3(5):597-603(2010)Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)Zhou, J., et al. J. Biol. Chem. 284(15):9648-9655(2009)Veluthakal, R., et al. Diabetes 56(1):204-210(2007)Armstrong, S.A., et al. J. Biol. Chem. 270(14):7864-7868(1995)

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$ 80.00
Cat# BP18056a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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