|Other Names||Glycine N-methyltransferase, GNMT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.|
|Tissue Location||Abundant in liver.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is an enzyme thatcatalyzes the conversion of S-adenosyl-L-methionine (along withglycine) to S-adenosyl-L-homocysteine and sarcosine. The encodedprotein is found in the cytoplasm and acts as a homotetramer.Defects in this gene are a cause of GNMT deficiency(hypermethioninemia).
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Lee, C.M., et al. Gene 443 (1-2), 151-157 (2009) :Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)Yen, C.H., et al. Toxicol. Appl. Pharmacol. 235(3):296-304(2009)Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.