|Other Names||Vasorin, Protein slit-like 2, VASN, SLITL2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as an inhibitor of TGF-beta signaling.|
|Cellular Location||Membrane; Single-pass type I membrane protein Secreted|
|Tissue Location||Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells|
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Provided below are standard protocols that you may find useful for product applications.
VASN may act as an inhibitor of TGF-beta signaling.
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)Ikeda, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 101(29):10732-10737(2004)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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