MS4A12 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NXJ0 |
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Clone Names | 110811131 |
Gene ID | 54860 |
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Other Names | Membrane-spanning 4-domains subfamily A member 12, MS4A12 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MS4A12 |
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Function | May be involved in signal transduction as a component of a multimeric receptor complex. |
Cellular Location | Membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a cell surface proteinfound primarily in the apical membrane of colonocytes. Silencing ofthis gene in colon cancer cells inhibits the proliferation, cellmotility, and chemotactic invasion of cells. This gene is part of acluster of similar genes found on chromosome 11. Two transcriptvariants encoding different isoforms have been found for this gene.
References
Koslowski, M., et al. Mol. Cancer 8, 77 (2009) :Koslowski, M., et al. Cancer Res. 68(9):3458-3466(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Liang, Y., et al. Immunogenetics 53(5):357-368(2001)Liang, Y., et al. Genomics 72(2):119-127(2001)
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