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GTF2IRD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UHL9
Clone Names 90121142
Peptide ID 90121142
Additional Information
Gene ID 9569
Other Names General transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, General transcription factor III, MusTRD1/BEN, Muscle TFII-I repeat domain-containing protein 1, Slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, Williams-Beuren syndrome chromosomal region 11 protein, Williams-Beuren syndrome chromosomal region 12 protein, GTF2IRD1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).
Cellular Location Nucleus.
Tissue Location Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested
Research Areas
Citations (0)

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The protein encoded by this gene contains five GTF2I-likerepeats and each repeat possesses a potential helix-loop-helix(HLH) motif. It may have the ability to interact with otherHLH-proteins and function as a transcription factor or as apositive transcriptional regulator under the control ofRetinoblastoma protein. This gene plays a role in craniofacial andcognitive development and mutations have been associated withWilliams-Beuren syndrome, a multisystem developmental disordercaused by deletion of multiple genes at 7q11.23. Alternativesplicing results in multiple transcript variants. [provided byRefSeq].


Antonell, A., et al. J. Med. Genet. 47(5):312-320(2010)Palmer, S.J., et al. J. Biol. Chem. 285(7):4715-4724(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Dai, L., et al. Am. J. Med. Genet. A 149A (3), 302-314 (2009) :Lazebnik, M.B., et al. J. Biol. Chem. 283(17):11078-11082(2008)

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$ 80.00
Cat# BP18120a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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