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SNAP25 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P60880
Clone Names 90504152
Peptide ID 90504152
Additional Information
Gene ID 6616
Other Names Synaptosomal-associated protein 25, SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein, SNAP25, SNAP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNAP25
Synonyms SNAP
Function t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
Cellular Location Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region (By similarity).
Tissue Location Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum
Research Areas
Citations (0)

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Synaptic vesicle membrane docking and fusion is mediatedby SNAREs (soluble N-ethylmaleimide-sensitive factor attachmentprotein receptors) located on the vesicle membrane (v-SNAREs) andthe target membrane (t-SNAREs). The assembled v-SNARE/t-SNAREcomplex consists of a bundle of four helices, one of which issupplied by v-SNARE and the other three by t-SNARE. For t-SNAREs onthe plasma membrane, the protein syntaxin supplies one helix andthe protein encoded by this gene contributes the other two.Therefore, this gene product is a presynaptic plasma membraneprotein involved in the regulation of neurotransmitter release. Twoalternative transcript variants encoding different protein isoformshave been described for this gene.


Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)Oner, O., et al. J Atten Disord (2010) In press :Zhang, H., et al. Eur. J. Paediatr. Neurol. (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

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$ 80.00
Cat# BP18126c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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