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SIK2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H0K1
Clone Names 90625066
Peptide ID 90625066
Additional Information
Gene ID 23235
Other Names Serine/threonine-protein kinase SIK2, Qin-induced kinase, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2, SIK2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIK2
Function Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

References

Ahmed, A.A., et al. Cancer Cell 18(2):109-121(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Nagel, S., et al. Leuk. Lymphoma 51(5):881-891(2010)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Katoh, Y., et al. Eur. J. Biochem. 271(21):4307-4319(2004)

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$ 80.00
Cat# BP18127c
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