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FIL1L Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q4L180
Clone Names 91113147
Peptide ID 91113147
Additional Information
Gene ID 11259
Other Names Filamin A-interacting protein 1-like, 130 kDa GPBP-interacting protein, 90 kDa GPBP-interacting protein, Protein down-regulated in ovarian cancer 1, DOC-1, FILIP1L, COL4A3BPIP, DOC1, GIP90
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FILIP1L
Synonyms COL4A3BPIP, DOC1, GIP90
Function Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature.
Cellular Location Cytoplasm. Membrane. Nucleus
Tissue Location Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer
Research Areas
Citations (0)

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Background

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.

References

Notaridou, M., et al. Int. J. Cancer (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Quaye, L., et al. Hum. Mol. Genet. 18(10):1869-1878(2009)Tandle, A.T., et al. Cytokine 30(6):347-358(2005)Mok, S.C., et al. Gynecol. Oncol. 52(2):247-252(1994)

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$ 80.00
Cat# BP18152a
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