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ORNT2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BXI2 |
|---|---|
| Clone Names | 91113095 |
| Gene ID | 83884 |
|---|---|
| Other Names | Mitochondrial ornithine transporter 2, Solute carrier family 25 member 2, SLC25A2, ORNT2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC25A2 (HGNC:22921) |
|---|---|
| Function | Mitochondrial transporter of the positively charged amino acids ornithine, lysine and arginine, and the neutral amino acid citrulline (PubMed:12807890). In addition, transports the basic amino acids histidine, homoarginine, and asymmetric dimethylarginine (aDMA), but not symmetric DMA, and the D-forms of lysine, arginine, ornithine and histidine (PubMed:26403849, PubMed:12807890). Functions by both counter-exchange and uniport mechanisms (PubMed:26403849). |
| Cellular Location | Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in liver, testis, spleen, lung, pancreas, and small intestine and expressed poorly in other tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Located between the protocadherin beta and gamma geneclusters on chromosome 5, this intronless gene encodes a proteinthat is highly similar to an ornithine transporter localized in themitochondrial inner membrane. The encoded protein most likely playsa role in metabolism as a mitochondrial transport protein.
References
Trynka, G., et al. Gut 58(8):1078-1083(2009)Fiermonte, G., et al. J. Biol. Chem. 278(35):32778-32783(2003)Camacho, J.A., et al. Mol. Genet. Metab. 79(4):257-271(2003)Wu, Q., et al. Genome Res. 11(3):389-404(2001)Porter, R.K. Biochim. Biophys. Acta 1459 (2-3), 356-362 (2000) :
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