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TFG Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q92734 |
|---|---|
| Clone Names | 90904167 |
| Gene ID | 10342 |
|---|---|
| Other Names | Protein TFG, TRK-fused gene protein, TFG |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TFG |
|---|---|
| Function | Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858). |
| Cellular Location | Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:27813252, PubMed:21478858). |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
There are several documented fusion oncoproteins encodedpartially by this gene. This gene also participates in severaloncogenic rearrangements resulting in anaplastic lymphoma andmixoid chondrosarcoma, and may play a role in the NF-kappaBpathway. Multiple transcript variants have been found for thisgene.
References
Miranda, C., et al. J. Cell. Physiol. 208(1):154-160(2006)Roccato, E., et al. J. Biol. Chem. 280(5):3382-3389(2005)Hisaoka, M., et al. Genes Chromosomes Cancer 40(4):325-328(2004)Roccato, E., et al. Br. J. Cancer 87(6):645-653(2002)Hernandez, L., et al. Am. J. Pathol. 160(4):1487-1494(2002)
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