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PCMTD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96MG8
Clone Names 100107101
Additional Information
Gene ID 115294
Other Names Protein-L-isoaspartate O-methyltransferase domain-containing protein 1, PCMTD1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCMTD1 (HGNC:30483)
Function Substrate recognition component of an ECS (Elongin BC-CUL5- SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:35486881). Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity (PubMed:35486881). May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein (PubMed:35486881).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P22061}. Membrane; Lipid-anchor
Research Areas
Citations (0)
citation

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Background

PCMTD1 belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :

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$ 277.78
Cat# BP18176a
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