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ENPP4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y6X5 |
|---|---|
| Clone Names | 91009013 |
| Gene ID | 22875 |
|---|---|
| Other Names | Bis(5'-adenosyl)-triphosphatase ENPP4, AP3A hydrolase, AP3Aase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 4, E-NPP 4, NPP-4, ENPP4, KIAA0879, NPP4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENPP4 |
|---|---|
| Synonyms | KIAA0879, NPP4 |
| Function | Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed on the surface of vascular endothelia. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ENPP4 belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Gijsbers, R., et al. J. Biol. Chem. 276(2):1361-1368(2001)
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