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PIGS Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96S52
Clone Names 100324239
Peptide ID 100324239
Additional Information
Gene ID 94005
Other Names GPI transamidase component PIG-S, Phosphatidylinositol-glycan biosynthesis class S protein, PIGS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIGS
Function Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

This gene encodes a protein that is involved in GPI-anchorbiosynthesis. The glycosylphosphatidylinositol (GPI) anchor is aglycolipid found on many blood cells and serves to anchor proteinsto the cell surface. This gene encodes an essential component ofthe multisubunit enzyme, GPI transamidase. GPI transamidasemediates GPI anchoring in the endoplasmic reticulum, by catalyzingthe transfer of fully assembled GPI units to proteins. [provided byRefSeq].

References

Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Hong, Y., et al. Mol. Biol. Cell 14(5):1780-1789(2003)Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)Vainauskas, S., et al. J. Biol. Chem. 277(34):30535-30542(2002)

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$ 80.00
Cat# BP18217b
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