|Other Names||GPI transamidase component PIG-S, Phosphatidylinositol-glycan biosynthesis class S protein, PIGS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is involved in GPI-anchorbiosynthesis. The glycosylphosphatidylinositol (GPI) anchor is aglycolipid found on many blood cells and serves to anchor proteinsto the cell surface. This gene encodes an essential component ofthe multisubunit enzyme, GPI transamidase. GPI transamidasemediates GPI anchoring in the endoplasmic reticulum, by catalyzingthe transfer of fully assembled GPI units to proteins. [provided byRefSeq].
Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Hong, Y., et al. Mol. Biol. Cell 14(5):1780-1789(2003)Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)Vainauskas, S., et al. J. Biol. Chem. 277(34):30535-30542(2002)
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