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PLEKHA1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HB21
Clone Names 100324051
Peptide ID 100324051
Additional Information
Gene ID 59338
Other Names Pleckstrin homology domain-containing family A member 1, PH domain-containing family A member 1, Tandem PH domain-containing protein 1, TAPP-1, PLEKHA1, TAPP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TAPP1
Function Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2
Tissue Location Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon
Research Areas
Citations (0)

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This gene encodes a pleckstrin homology domain-containingadapter protein. The encoded protein is localized to the plasmamembrane where it specifically binds phosphatidylinositol3,4-bisphosphate. This protein may be involved in the formation ofsignaling complexes in the plasma membrane. Polymorphisms in thisgene are associated with age-related macular degeneration.Alternate splicing results in multiple transcript variants. Apseudogene of this gene is found on chromosome 5.


Deangelis, M.M., et al. Ophthalmology 115(7):1209-1215(2008)Manna, D., et al. J. Biol. Chem. 282(44):32093-32105(2007)Kanda, A., et al. Proc. Natl. Acad. Sci. U.S.A. 104(41):16227-16232(2007)Leveziel, N., et al. Mol. Vis. 13, 2153-2159 (2007) :Hogan, A., et al. J. Biol. Chem. 279(51):53717-53724(2004)

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$ 80.00
Cat# BP18230c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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