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GNPTG Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UJJ9
Clone Names 110617270
Peptide ID 110617270
Additional Information
Gene ID 84572
Other Names N-acetylglucosamine-1-phosphotransferase subunit gamma, GlcNAc-1-phosphotransferase subunit gamma, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, GNPTG, C16orf27, GNPTAG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C16orf27, GNPTAG
Function Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine- 1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.
Cellular Location Secreted. Golgi apparatus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene encodes the gamma sunbunit of theN-acetylglucosamine-1-phosphotransferase complex. This hexamericcomplex, composed of alpha, beta and gamma subunits, catalyzes thefirst step in synthesis of a mannose 6-phosphate lysosomalrecognition marker. This enzyme complex is necessary for targetingof lysosomal hydrolases to the lysosome. Mutations in the geneencoding the gamma subunit have been associated with mucolipidosisIIIC, also known as mucolipidosis III gamma.


Kang, C., et al. N. Engl. J. Med. 362(8):677-685(2010)Qian, Y., et al. J. Biol. Chem. 285(5):3360-3370(2010)Pohl, S., et al. Am. J. Med. Genet. A 152A (1), 124-132 (2010) :Encarnacao, M., et al. Clin. Genet. 76(1):76-84(2009)Persichetti, E., et al. Hum. Mutat. 30(6):978-984(2009)

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$ 80.00
Cat# BP18233b
Availability: In Stock
Bulk Size
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