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LBX1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P52954
Clone Names 110729124
Peptide ID 110729124
Additional Information
Other Names Transcription factor LBX1, Ladybird homeobox protein homolog 1, LBX1, LBX1H
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LBX1
Synonyms LBX1H
Function Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.
Cellular Location Nucleus. EMBL; X90828; CAA62342.1; -; mRNA EMBL; AL135794; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471066; EAW49777.1; -; Genomic_DNA EMBL; BC069156; AAH69156.1; -; mRNA EMBL; BC136321; AAI36322.1; -; mRNA CCDS; CCDS31270.1; - RefSeq; NP_006553.2; NM_006562.4 UniGene; Hs.37128; - ProteinModelPortal; P52954; - SMR; P52954; - BioGrid; 115903; 1 IntAct; P52954; 23 STRING; 9606.ENSP00000359212; - iPTMnet; P52954; - PhosphoSitePlus; P52954; - BioMuta; LBX1; - DMDM; 117949813; - PaxDb; P52954; - PeptideAtlas; P52954; - PRIDE; P52954; - ProteomicsDB; 56564; - Ensembl; ENST00000370193; ENSP00000359212; ENSG00000138136 GeneID; 10660; - KEGG; hsa:10660; - UCSC; uc001ksx.4; human CTD; 10660; - DisGeNET; 10660; - EuPathDB; HostDB:ENSG00000138136.6; - GeneCards; LBX1; - HGNC; HGNC:16960; LBX1 HPA; HPA002016; - HPA; HPA002086; - MIM; 604255; gene neXtProt; NX_P52954; - OpenTargets; ENSG00000138136; - PharmGKB; PA142671561; - eggNOG; KOG0488; Eukaryota eggNOG; ENOG411188D; LUCA GeneTree; ENSGT00910000143996; - HOGENOM; HOG000007247; - HOVERGEN; HBG006244; - InParanoid; P52954; - KO; K09353; - OMA; HTTSKEC; - OrthoDB; EOG091G09CY; - PhylomeDB; P52954; - TreeFam; TF325047; - SIGNOR; P52954; - GeneWiki; LBX1; - GenomeRNAi; 10660; - PRO; PR:P52954; - Proteomes; UP000005640; Chromosome 10 Bgee; ENSG00000138136; - CleanEx; HS_LBX1; - Genevisible; P52954; HS GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0005667; C:transcription factor complex; IEA:Ensembl GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc GO; GO:0001947; P:heart looping; IEA:Ensembl GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl GO; GO:0048664; P:neuron fate determination; IEA:Ensembl GO; GO:0021920; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification; IEA:Ensembl GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW CDD; cd00086; homeodomain; 1 InterPro; IPR009057; Homeobox-like_sf InterPro; IPR017970; Homeobox_CS InterPro; IPR001356; Homeobox_dom InterPro; IPR000047; HTH_motif Pfam; PF00046; Homeobox; 1 PRINTS; PR00031; HTHREPRESSR SMART; SM00389; HOX; 1 SUPFAM; SSF46689; SSF46689; 1 PROSITE; PS00027; HOMEOBOX_1; 1 PROSITE; PS50071; HOMEOBOX_2; 1 2: Evidence at transcript level; Complete proteome; Developmental protein; Differentiation; DNA-binding; Homeobox; Myogenesis; Neurogenesis; Nucleus; Reference proteome; Transcription; Transcription regulation CHAIN 1 281 Transcription factor LBX1 /FTId=PRO_0000049166 DNA_BIND 125 184 Homeobox. {ECO:0000255|PROSITE- ProRule:PRU00108} COMPBIAS 220 226 Poly-Gly COMPBIAS 270 281 Asp/Glu-rich (highly acidic) CONFLICT 33 72 LTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHAQGGLP -> YAVQHRGHPQQAVRAEKLLAAWGGAPAGRRGQARAGRL A (in Ref. 1; CAA62342). CONFLICT 81 81 Q -> K (in Ref. 1; CAA62342) CONFLICT 183 183 D -> E (in Ref. 1; CAA62342) CONFLICT 194 194 A -> P (in Ref. 1; CAA62342) CONFLICT 247 248 AG -> RC (in Ref. 1; CAA62342) SEQUENCE 281 AA; 30221 MW; 8467F2B515681CCA CRC64; MTSKEDGKAA PGEERRRSPL DHLPPPANSN KPLTPFSIED ILNKPSVRRS YSLCGAAHLL AAADKHAQGG LPLAGRALLS QTSPLCALEE LASKTFKGLE VSVLQAAEGR DGMTIFGQRQ TPKKRRKSRT AFTNHQIYEL EKRFLYQKYL SPADRDQIAQ QLGLTNAQVI TWFQNRRAKL KRDLEEMKAD VESAKKLGPS GQMDIVALAE LEQNSEATAG GGGGCGRAKS RPGSPVLPPG APKAPGAGAL QLSPASPLTD QPASSQDCSE DEEDEEIDVD D
Research Areas
Citations (0)

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This gene and the orthologous mouse gene were found bytheir homology to the Drosophila lady bird early and late homeoboxgenes. In the mouse, this gene is a key regulator of muscleprecursor cell migration and is required for the acquisition ofdorsal identities of forelimb muscles.


Yu, M., et al. Genes Dev. 23(15):1737-1742(2009)Deloukas, P., et al. Nature 429(6990):375-381(2004)de Mollerat, X.J., et al. Hum. Mol. Genet. 12(16):1959-1971(2003)Kozmik, Z., et al. Genesis 29(4):172-179(2001)Jagla, K., et al. Mech. Dev. 53(3):345-356(1995)

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$ 80.00
Cat# BP18241c
Availability: In Stock
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