|Other Names||Transcription factor LBX1, Ladybird homeobox protein homolog 1, LBX1, LBX1H|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.|
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Provided below are standard protocols that you may find useful for product applications.
This gene and the orthologous mouse gene were found bytheir homology to the Drosophila lady bird early and late homeoboxgenes. In the mouse, this gene is a key regulator of muscleprecursor cell migration and is required for the acquisition ofdorsal identities of forelimb muscles.
Yu, M., et al. Genes Dev. 23(15):1737-1742(2009)Deloukas, P., et al. Nature 429(6990):375-381(2004)de Mollerat, X.J., et al. Hum. Mol. Genet. 12(16):1959-1971(2003)Kozmik, Z., et al. Genesis 29(4):172-179(2001)Jagla, K., et al. Mech. Dev. 53(3):345-356(1995)
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