|Other Names||Probable E3 ubiquitin-protein ligase RNF217, 632-, IBR domain-containing protein 1, RING finger protein 217, RNF217, C6orf172, IBRDC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|
|Cellular Location||Membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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