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SGPP2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IWX5
Clone Names 110808272
Peptide ID 110808272
Additional Information
Gene ID 130367
Other Names Sphingosine-1-phosphate phosphatase 2, SPPase2, Spp2, hSPP2, 313-, Sphingosine-1-phosphatase 2, SGPP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SGPP2
Function Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes.
Research Areas
Citations (0)

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Sphingosine-1-phosphate (S1P) is a bioactive sphingolipidmetabolite that regulates diverse biologic processes. SGPP2catalyzes the degradation of S1P (Ogawa et al., 2003 [PubMed12411432]).


Mechtcheriakova, D., et al. Cell. Signal. 19(4):748-760(2007)Ogawa, C., et al. J. Biol. Chem. 278(2):1268-1272(2003)

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$ 80.00
Cat# BP18254a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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