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DUS2L Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NX74
Clone Names 110811063
Peptide ID 110811063
Additional Information
Gene ID 54920
Other Names tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUS2
Synonyms DUS2L
Function Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Cellular Location Cytoplasm. Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum
Tissue Location Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level).
Research Areas
Citations (0)

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Dihydrouridine synthase catalyzes reduction of the5,6-double bond of a uridine residue on the displacement loop oftRNA. The resultant modified base, 5,6-dihydrouridine, appears toincrease the conformational flexibility and dynamic motion of tRNA(Kato et al., 2005 [PubMed 15994936]).


Mittelstadt, M., et al. Nucleic Acids Res. 36(3):998-1008(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Kato, T., et al. Cancer Res. 65(13):5638-5646(2005)

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$ 80.00
Cat# BP18265b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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