|Other Names||Fatty acid desaturase 3, 11419-, Cytochrome b5-related protein, FADS3, CYB5RP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Has been found in heart, liver, lung, uterus, and brainstem.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the fattyacid desaturase (FADS) gene family. Desaturase enzymes regulateunsaturation of fatty acids through the introduction of doublebonds between defined carbons of the fatty acyl chain. FADS familymembers are considered fusion products composed of an N-terminalcytochrome b5-like domain and a C-terminal multiplemembrane-spanning desaturase portion, both of which arecharacterized by conserved histidine motifs. This gene is clusteredwith family members FADS1 and FADS2 at 11q12-q13.1; this cluster isthought to have arisen evolutionarily from gene duplication basedon its similar exon/intron organization.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Mathias, R.A., et al. J. Lipid Res. 51(9):2766-2774(2010)Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Hicks, A.A., et al. PLoS Genet. 5 (10), E1000672 (2009) :
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