|Other Names||Mitochondrial ribosome-associated GTPase 2, GTP-binding protein 5, Protein obg homolog 1, ObgH1, MTG2, GTPBP5, OBGH1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays GTPase activity. Involved in the ribosome maturation process.|
|Cellular Location||Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side|
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Provided below are standard protocols that you may find useful for product applications.
Small G proteins, such as GTPBP5, act as molecularswitches that play crucial roles in the regulation of fundamentalcellular processes such as protein synthesis, nuclear transport,membrane trafficking, and signal transduction (Hirano et al., 2006[PubMed 17054726]).
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hirano, Y., et al. Genes Cells 11(11):1295-1304(2006)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Deloukas, P., et al. Nature 414(6866):865-871(2001)
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