NRBF2 Antibody (Center-2) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96F24 |
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Clone Names | 81231006 |
Gene ID | 29982 |
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Other Names | Nuclear receptor-binding factor 2, NRBF-2, Comodulator of PPAR and RXR, NRBF2, COPR |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1828e was selected from the Center-2 region of human NRBF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NRBF2 |
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Synonyms | COPR |
Function | May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9QYK3}. Cytoplasm {ECO:0000250|UniProtKB:Q9QYK3}. Cytoplasmic vesicle. Cytoplasmic vesicle, autophagosome |
Tissue Location | Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852). |
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Provided below are standard protocols that you may find useful for product applications.
Background
NRBF2 may modulate transcriptional activation by target nuclear receptors. It can act as transcriptional activator (in vitro).
References
Daub H., Olsen J.V.Mol. Cell 31:438-448(2008)Flores A.M.J. Invest. Dermatol. 123:1092-1101(2004) Wiemann S., Weil B.Genome Res. 11:422-435(2001)
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