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ZFP57 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NU63
Clone Names 110811266
Peptide ID 110811266
Additional Information
Gene ID 346171
Other Names Zinc finger protein 57 homolog, Zfp-57, Zinc finger protein 698, ZFP57, C6orf40, ZNF698
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZFP57
Synonyms C6orf40, ZNF698
Function Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Cellular Location Nucleus. Note=Binds various differentially methylated regions (DMR), including the SNRPN DMR
Research Areas
Citations (0)

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The protein encoded by this gene is a zinc finger proteincontaining a KRAB domain. Studies in mouse suggest that thisprotein may function as a transcriptional repressor. Mutations inthis gene have been associated with transient neonatal diabetesmellitus type 1 (TNDM1).


Spengler, S., et al. Eur J Med Genet 52(6):415-416(2009)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Tse, K.P., et al. Am. J. Hum. Genet. 85(2):194-203(2009)Li, X., et al. Dev. Cell 15(4):547-557(2008)Mackay, D.J., et al. Nat. Genet. 40(8):949-951(2008)

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$ 80.00
Cat# BP18299c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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