SLC17A4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y2C5 |
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Clone Names | 110811211 |
Gene ID | 10050 |
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Other Names | Probable small intestine urate exporter, Solute carrier family 17 member 4, SLC17A4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC17A4 |
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Function | Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions (PubMed:22460716). Mediates chloride-dependent transport of urate (PubMed:22460716). Mediates sodium-independent high affinity transport of thyroid hormones including L-thyroxine (T4) and 3,3',5-triiodo-L- thyronine (T3) (PubMed:30367059, PubMed:34937426). Can actively transport inorganic phosphate into cells via Na(+) cotransport (PubMed:22460716). |
Cellular Location | Apical cell membrane; Multi-pass membrane protein. Note=Apical in the intestinal brush border |
Tissue Location | Abundantly expressed in pancreas, liver, colon and small intestine, less in kidney. Not detected in the adrenal glands, brain, placenta, heart, testis, skeletal muscle, and lungs |
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Provided below are standard protocols that you may find useful for product applications.
Background
SLC17A4 may be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity).
References
Elmariah, S., et al. Am. J. Physiol., Cell Physiol. 285 (2), C446-C456 (2003) :Shibui, A., et al. J. Hum. Genet. 44(3):190-192(1999)
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