|Other Names||Probable small intestine urate exporter, Solute carrier family 17 member 4, SLC17A4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro).|
|Cellular Location||Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Apical in the intestinal brush border|
|Tissue Location||Abundantly expressed in pancreas, liver, colon and small intestine, less in kidney. Not detected in the adrenal glands, brain, placenta, heart, testis, skeletal muscle, and lungs.|
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Provided below are standard protocols that you may find useful for product applications.
SLC17A4 may be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity).
Elmariah, S., et al. Am. J. Physiol., Cell Physiol. 285 (2), C446-C456 (2003) :Shibui, A., et al. J. Hum. Genet. 44(3):190-192(1999)
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