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C5orf4 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96IV6
Clone Names 110808089
Additional Information
Gene ID 10826
Other Names Fatty acid hydroxylase domain-containing protein 2, FAXDC2, C5orf4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAXDC2
Synonyms C5orf4
Function Promotes megakaryocyte differentiation by enhancing ERK phosphorylation and up-regulating RUNX1 expression.
Cellular Location Cytoplasm. Membrane; Multi-pass membrane protein
Tissue Location Down-regulated in primary acute myeloid leukemia (AML) patients.
Research Areas
Citations (0)
citation

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Background

C5ORF4 belongs to the Sterol Desaturase family. It's function remains unknown. The Sterol Desaturase family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis of a plant cuticular wax. These enzymes contain many conserved histidine residues. Members of this family are integral membrane proteins. C5ORF4 has been identified as a putative tumour suppressor.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Boultwood, J., et al. Genomics 66(1):26-34(2000)

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$ 277.78
Cat# BP18309c
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