C5orf4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96IV6 |
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Clone Names | 110808089 |
Gene ID | 10826 |
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Other Names | Fatty acid hydroxylase domain-containing protein 2, FAXDC2, C5orf4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FAXDC2 |
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Synonyms | C5orf4 |
Function | Promotes megakaryocyte differentiation by enhancing ERK phosphorylation and up-regulating RUNX1 expression. |
Cellular Location | Cytoplasm. Membrane; Multi-pass membrane protein |
Tissue Location | Down-regulated in primary acute myeloid leukemia (AML) patients. |
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Provided below are standard protocols that you may find useful for product applications.
Background
C5ORF4 belongs to the Sterol Desaturase family. It's function remains unknown. The Sterol Desaturase family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis of a plant cuticular wax. These enzymes contain many conserved histidine residues. Members of this family are integral membrane proteins. C5ORF4 has been identified as a putative tumour suppressor.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Boultwood, J., et al. Genomics 66(1):26-34(2000)
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