GSX2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BZM3 |
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Clone Names | 110811093 |
Gene ID | 170825 |
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Other Names | GS homeobox 2, Homeobox protein GSH-2, GSX2, GSH2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GSX2 |
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Synonyms | GSH2 |
Function | Transcription factor that binds 5'-CNAATTAG-3' DNA sequence and regulates the expression of numerous genes including genes important for brain development (PubMed:31412107). During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, necessary and sufficient to correctly specify the ventral lateral ganglionic eminence (LGE) and its major derivatives, the striatal projection neurons. At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:31412107}. Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
GSX2 is probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3' (By similarity).
References
Waclaw, R.R., et al. Neuron 63(4):451-465(2009)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Dauwerse, J.G., et al. J. Med. Genet. 39(9):686-688(2002)Cools, J., et al. Blood 99(5):1776-1784(2002)
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