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BARON Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92622
Additional Information
Gene ID 9711
Other Names Run domain Beclin-1 interacting and cysteine-rich containing protein, Rubicon, Beclin-1 associated RUN domain containing protein, Baron, KIAA0226
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RUBCN (HGNC:28991)
Synonyms KIAA0226
Function Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).
Cellular Location Late endosome. Lysosome. Early endosome Note=Predominantly located in late endosomes/lysosomes, only partially detected in early endosome and not at all in the Golgi apparatus
Research Areas
Citations (0)
citation

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References

Matsunaga, K., et al. Nat. Cell Biol. 11(4):385-396(2009)Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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$ 277.78
Cat# BP1831c
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