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SLC38A2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96QD8
Clone Names 100318186
Peptide ID 100318186
Additional Information
Gene ID 54407
Other Names Sodium-coupled neutral amino acid transporter 2, Amino acid transporter A2, Protein 40-9-1, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2, SLC38A2, ATA2, KIAA1382, SAT2, SNAT2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC38A2
Synonyms ATA2, KIAA1382, SAT2, SNAT2
Function Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood- brain barrier and in the supply of maternal nutrients to the fetus through the placenta.
Cellular Location Cell membrane; Multi-pass membrane protein Note=Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.
Tissue Location Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).
Research Areas
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Background

SLC38A2 functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.

References

Lewis, R.M., et al. Placenta 31(5):418-422(2010)Jones, H.N., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1228-C1235 (2009) :Zhang, Z., et al. J. Biol. Chem. 284(37):25314-25323(2009)Iruloh, C.G., et al. Pediatr. Res. 65(1):51-56(2009)Gjymishka, A., et al. J. Biol. Chem. 283(41):27736-27747(2008)

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$ 80.00
Cat# BP18342b
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