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ANO1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q5XXA6
Clone Names 100427180
Peptide ID 100427180
Additional Information
Gene ID 55107
Other Names Anoctamin-1, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, ANO1, DOG1, ORAOV2, TAOS2, TMEM16A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANO1
Synonyms DOG1, ORAOV2, TAOS2, TMEM16A
Function Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors
Tissue Location Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles
Research Areas
Citations (0)

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ANO1 acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Barro-Soria, R., et al. Pflugers Arch. 459(3):485-497(2010)Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Ferrera, L., et al. J. Biol. Chem. 284(48):33360-33368(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP18347c
(40 western blots)
Availability: In Stock
Bulk Size
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