|Other Names||Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.|
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NPBWR1 interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :Cottrell, S., et al. J. Urol. 177(5):1753-1758(2007)Mazzocchi, G., et al. J. Clin. Endocrinol. Metab. 90(6):3466-3471(2005)Zaratin, P.F., et al. Mol. Cell. Neurosci. 28(1):55-63(2005)
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