|Other Names||Protein-arginine deiminase type-6, Peptidyl arginine deiminase-like protein, Peptidylarginine deiminase VI, hPADVI, Protein-arginine deiminase type VI, PADI6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo (By similarity).|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Ovary, testis and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Peptidylarginine deiminases (PADs, EC 220.127.116.11), includingPADI6, make up a family of posttranslational protein modificationenzymes that convert arginine residues to citrulline residues inthe presence of calcium ions.
Stacey, S.N., et al. Nat. Genet. 40(11):1313-1318(2008)Chavanas, S., et al. Gene 330, 19-27 (2004) :Zhang, J., et al. Acta Biochim. Pol. 51(4):1051-1058(2004)Vossenaar, E.R., et al. Bioessays 25(11):1106-1118(2003)
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