Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
PADI6 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6TGC4 |
|---|---|
| Clone Names | 110729169 |
| Gene ID | 353238 |
|---|---|
| Other Names | Protein-arginine deiminase type-6, Peptidyl arginine deiminase-like protein, Peptidylarginine deiminase VI, hPADVI, Protein-arginine deiminase type VI, PADI6 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PADI6 |
|---|---|
| Synonyms | PAD6 |
| Function | Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:27545678). |
| Cellular Location | Cytoplasm. Nucleus {ECO:0000250|UniProtKB:Q8K3V4}. Cytoplasmic vesicle, secretory vesicle, Cortical granule {ECO:0000250|UniProtKB:Q8K3V4}. Note=Predominantly cytoplasmic (oocyte cytoplasmic sheets), also nuclear. Released extracellularly during the cortical reaction, and remains associated with the blastomeres surfaces as a peripheral membrane protein until the blastocyst stage of development. {ECO:0000250|UniProtKB:Q8K3V4} |
| Tissue Location | Highly expressed in oocytes and weakly expressed in other somatic tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Peptidylarginine deiminases (PADs, EC 3.5.3.15), includingPADI6, make up a family of posttranslational protein modificationenzymes that convert arginine residues to citrulline residues inthe presence of calcium ions.
References
Stacey, S.N., et al. Nat. Genet. 40(11):1313-1318(2008)Chavanas, S., et al. Gene 330, 19-27 (2004) :Zhang, J., et al. Acta Biochim. Pol. 51(4):1051-1058(2004)Vossenaar, E.R., et al. Bioessays 25(11):1106-1118(2003)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
