|Other Names||Nuclear RNA export factor 5, TAP-like protein 1, TAPL-1, NXF5, TAPL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons.|
|Cellular Location||Cytoplasm. Nucleus. Note=Mainly localized in the cytoplasm of cells and more particularly in the cell body and neurites of hippocampal neurons. Although nuclear localization is also observed. Not detected at nuclear rim|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene is one member of a family of nuclear RNA exportfactor genes. The encoded protein can bind RNA, and is implicatedin mRNA nuclear export. However, this protein has lost severalC-terminal protein domains found in other family members that arerequired for export activity, and may be an evolving pseudogene.Alternatively spliced transcript variants have been described, butmost are candidates for nonsense-mediated decay (NMD) and may notexpress proteins in vivo.
Tarpey, P.S., et al. Nat. Genet. 41(5):535-543(2009)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :Frints, S.G., et al. Am. J. Med. Genet. A 119A (3), 367-374 (2003) :Jun, L., et al. Curr. Biol. 11(18):1381-1391(2001)Herold, A., et al. Mol. Cell. Biol. 20(23):8996-9008(2000)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.