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OSBPL10 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BXB5
Clone Names 110811151
Peptide ID 110811151
Additional Information
Gene ID 114884
Other Names Oxysterol-binding protein-related protein 10, ORP-10, OSBP-related protein 10, OSBPL10, ORP10, OSBP9
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name OSBPL10
Synonyms ORP10, OSBP9
Function Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable). Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302). Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437). Binds cholesterol and acidic phospholipids (PubMed:22906437). Also binds 25-hydroxycholesterol (PubMed:17428193). Binds phosphatidylserine (PubMed:23934110).
Cellular Location Cytoplasm, cytoskeleton Note=Associates with microtubules.
Research Areas
Citations (0)

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This gene encodes a member of the oxysterol-bindingprotein (OSBP) family, a group of intracellular lipid receptors.Like most members, the encoded protein contains an N-terminalpleckstrin homology domain and a highly conserved C-terminalOSBP-like sterol-binding domain. Multiple transcript variantsencoding different isoforms have been found for this gene.


Koriyama, H., et al. J. Atheroscler. Thromb. 17(10):1054-1062(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Koriyama, H., et al. Hypertens. Res. 33(5):511-514(2010)Perttila, J., et al. J. Mol. Med. 87(8):825-835(2009)Ma, J., et al. Atherosclerosis 191(1):63-72(2007)

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$ 80.00
Cat# BP18381b
Availability: In Stock
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