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SLC25A32 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H2D1 |
|---|---|
| Clone Names | 110811214 |
| Gene ID | 81034 |
|---|---|
| Other Names | Mitochondrial folate transporter/carrier, Solute carrier family 25 member 32, SLC25A32, MFT, MFTC |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC25A32 {ECO:0000303|PubMed:26933868, ECO:0000312|HGNC:HGNC:29683} |
|---|---|
| Function | Facilitates flavin adenine dinucleotide (FAD) translocation across the mitochondrial inner membrane into the mitochondrial matrix where it acts as a redox cofactor to assist flavoenzyme activities in fundamental metabolic processes including fatty acid beta-oxidation, amino acid and choline metabolism as well as mitochondrial electron transportation. In particular, provides FAD to DLD dehydrogenase of the glycine cleavage system, part of mitochondrial one-carbon metabolic pathway involved in neural tube closure in early embryogenesis. |
| Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Folate metabolism is distributed between the cytosolic andmitochondrial compartments. SLC25A32 is a transporter that shuttlesfolates from the cytoplasm into mitochondria (Titus and Moran, 2000[PubMed 10978331]).
References
Hull, M.L., et al. Fertil. Steril. 91 (6), 2732 (2009) :Titus, S.A., et al. J. Biol. Chem. 275(47):36811-36817(2000)
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