|Other Names||WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2, Growth and differentiation factor-associated serum protein 1, GASP-1, hGASP-1, WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2, GASP1, WFIKKNRP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).|
|Tissue Location||Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney|
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Provided below are standard protocols that you may find useful for product applications.
The WFIKKN1 protein contains a WAP domain, follistatindomain, immunoglobulin domain, two tandem Kunitz domains, and anNTR domain. This gene encodes a WFIKKN1-related protein which hasthe same domain organization as the WFIKKN1 protein. The WAP-type,follistatin type, Kunitz-type, and NTR-type protease inhibitorydomains may control the action of multiple types of proteases.
Saremi, A., et al. Mol. Cell. Endocrinol. 317 (1-2), 25-30 (2010) :Kondas, K., et al. J. Biol. Chem. 283(35):23677-23684(2008)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Hill, J.J., et al. Mol. Endocrinol. 17(6):1144-1154(2003)Nagy, A., et al. Eur. J. Biochem. 270(9):2101-2107(2003)
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