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SLU7 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95391
Clone Names 110717187
Peptide ID 110717187
Additional Information
Gene ID 10569
Other Names Pre-mRNA-splicing factor SLU7, hSlu7, SLU7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLU7
Function Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
Cellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules
Research Areas
Citations (0)

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Pre-mRNA splicing occurs in two sequentialtransesterification steps. The protein encoded by this gene is asplicing factor that has been found to be essential during thesecond catalytic step in the pre-mRNA splicing process. Itassociates with the spliceosome and contains a zinc knuckle motifthat is found in other splicing factors and is involved inprotein-nucleic acid and protein-protein interactions. [provided byRefSeq].


Alberstein, M., et al. RNA 13(11):1988-1999(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Shomron, N., et al. J. Cell. Sci. 118 (PT 6), 1151-1159 (2005) :Shomron, N., et al. Mol. Biol. Cell 15(8):3782-3795(2004)Chua, K., et al. Mol. Cell. Biol. 21(5):1509-1514(2001)

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$ 80.00
Cat# BP18404a
(40 western blots)
Availability: In Stock
Bulk Size
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