Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
FBXO44 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H4M3 |
|---|---|
| Clone Names | 110808003 |
| Gene ID | 93611 |
|---|---|
| Other Names | F-box only protein 44, F-box protein FBX30, F-box/G-domain protein 3, FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FBXO44 |
|---|---|
| Synonyms | FBG3, FBX30, FBX44, FBX6A, FBXO6A |
| Function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| Tissue Location | Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofthe ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into 3 classes: Fbwscontaining WD-40 domains, Fbls containing leucine-rich repeats, andFbxs containing either different protein-protein interactionmodules or no recognizable motifs. The protein encoded by this genebelongs to the Fbxs class. It is also a member of the NFB42 (neuralF Box 42 kDa) family, similar to F-box only protein 2 and F-boxonly protein 6. Four alternatively spliced transcript variantsencoding two distinct isoforms have been found for this gene.
References
Kumanomidou, T., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 1), 95-98 (2010) :Glenn, K.A., et al. J. Biol. Chem. 283(19):12717-12729(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)Ilyin, G.P., et al. Gene 296 (1-2), 11-20 (2002) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
