|Other Names||Golgin subfamily A member 6A, Golgin linked to PML, Golgin-like protein, GOLGA6A, GLP, GOLGA6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Highly expressed in seminiferous tubes in testis. Highly expressed in spermatids, barely detectable in late pachytene spermatocytes, and not detectable in spermatogonia Detected at intermediate levels in pancreas and lymph nodes, and at much lower levels in spleen, peripheral blood leukocytes, skeletal muscle, liver, lung, placenta, brain and heart|
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The Golgi apparatus, which participates in glycosylationand transport of proteins and lipids in the secretory pathway,consists of a series of stacked cisternae (flattened membranesacs). Interactions between the Golgi and microtubules are thoughtto be important for the reorganization of the Golgi after itfragments during mitosis. The protein encoded by this gene is amember of the golgin family of proteins, whose members localize tothe Golgi. This gene is found in a large, low copy repeat sequenceor duplicon that is found in multiple copies, that are greatherthan 90% similar, on chromosome 15. Duplicons are associated withdeletions, inversions and other chromosome rearrangements thatunderlie genomic disease. The protein encoded by this gene isthought to be a functional golgin protein while the majority of therelated copies of this gene are thought to be transcribedpseudogenes.
Ventura, M., et al. Genome Res. 13(9):2059-2068(2003)Pujana, M.A., et al. Eur. J. Hum. Genet. 10(1):26-35(2002)Gratacos, M., et al. Cell 106(3):367-379(2001)Pujana, M.A., et al. Genome Res. 11(1):98-111(2001)Gilles, F., et al. Genomics 70(3):364-374(2000)
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