|Other Names||Solute carrier family 52, riboflavin transporter, member 1, Porcine endogenous retrovirus A receptor 2, PERV-A receptor 2, Protein GPR172B, Riboflavin transporter 1, hRFT1, SLC52A1, GPR172B, PAR2, RFT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR172B, PAR2, RFT1|
|Function||Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.|
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Provided below are standard protocols that you may find useful for product applications.
GPCR41 (MIM 607882) and GPCR42 act as receptors forporcine endogenous retrovirus subgroup A (PERV-A).[supplied byOMIM].
Yonezawa, A., et al. Am. J. Physiol., Cell Physiol. 295 (3), C632-C641 (2008) :Ericsson, T.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(11):6759-6764(2003)Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :
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