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PAPD5 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NDF8
Clone Names 110808233
Peptide ID 110808233
Additional Information
Gene ID 64282
Other Names Non-canonical poly(A) RNA polymerase PAPD5, PAP-associated domain-containing protein 5, Terminal uridylyltransferase 3, TUTase 3, Topoisomerase-related function protein 4-2, TRF4-2, PAPD5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAPD5
Function Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
Cellular Location Nucleus, nucleolus. Cytoplasm. Note=Predominantly expressed in the cytoplasm
Research Areas
Citations (0)

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PAPD5 plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Mullen, T.E., et al. Genes Dev. 22(1):50-65(2008)Walowsky, C., et al. J. Biol. Chem. 274(11):7302-7308(1999)

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$ 80.00
Cat# BP18427a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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