|Other Names||CGG triplet repeat-binding protein 1, CGG-binding protein 1, 20 kDa CGG-binding protein, p20-CGGBP DNA-binding protein, CGGBP1, CGGBP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.|
|Tissue Location||Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
CGGBP1 influences expression of the FMR1 gene (MIM309550), which is associated with the fragile X mental retardationsyndrome (MIM 300624), by specifically interacting with the 5-prime(CGG)n-3-prime repeat in its 5-prime UTR.
Gulyi, P.V., et al. Tsitologiia 51(12):1005-1012(2009)Arrieta, I., et al. Hum. Biol. 80(6):593-600(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Naumann, F., et al. Genomics 83(1):106-118(2004)Chen, L.S., et al. Hum. Mol. Genet. 12(23):3067-3074(2003)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.