GYG2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O15488 |
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Clone Names | 110819068 |
Gene ID | 8908 |
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Other Names | Glycogenin-2, GN-2, GN2, GYG2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GYG2 |
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Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It self- glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. |
Tissue Location | Detected in liver (at protein level) (PubMed:9857012). Expressed preferentially in liver, heart, and pancreas (PubMed:9346895). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the the glycogenin family.Glycogenin is a self-glucosylating protein involved in theinitiation reactions of glycogen biosynthesis. A gene on chromosome3 encodes the muscle glycogenin and this X-linked gene encodes theglycogenin mainly present in liver; both are involved in bloodglucose homeostasis. This gene has a short version on chromosome Y,which is 3' truncated and can not make a functional protein.Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified.
References
Gibbons, B.J., et al. J. Mol. Biol. 319(2):463-477(2002)Harris, R.A., et al. Proteomics 2(2):212-223(2002)Zhai, L., et al. Gene 242 (1-2), 229-235 (2000) :Mu, J., et al. J. Biol. Chem. 273(52):34850-34856(1998)Orho, M., et al. J. Clin. Invest. 102(3):507-515(1998)
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