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FCRL1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96LA6 |
|---|---|
| Clone Names | 110826130 |
| Gene ID | 115350 |
|---|---|
| Other Names | Fc receptor-like protein 1, FcR-like protein 1, FcRL1, Fc receptor homolog 1, FcRH1, IFGP family protein 1, hIFGP1, Immune receptor translocation-associated protein 5, CD307a, FCRL1, FCRH1, IFGP1, IRTA5 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FCRL1 |
|---|---|
| Synonyms | FCRH1, IFGP1, IRTA5 |
| Function | May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B- cells (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the immunoglobulin receptorsuperfamily and is one of several Fc receptor-like glycoproteinsclustered on the long arm of chromosome 1. The encoded proteincontains three extracellular C2-like immunoglobulin domains, atransmembrane domain and a cytoplasmic domain with twoimmunoreceptor-tyrosine activation motifs. This protein may play arole in the regulation of cancer cell growth. Alternative splicingresults in multiple transcript variants.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kazemi, T., et al. Cancer Immunol. Immunother. 58(6):989-996(2009)Kazemi, T., et al. Int. J. Cancer 123(9):2113-2119(2008)Du, X., et al. Blood 111(1):338-343(2008)
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