|Other Names||Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type III membrane protein|
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Analysis of cDNA clones indicates that ribosome bindingprotein 1 may exist in different forms due to removal of tandemrepeats, or partial intraexonic splicing of RRBP1. The formpresented here is lacking the canine p180 ribosome-binding domain,NQGKKAEGAQ, which is tandemly repeated close to the N-terminus inother forms that haven't been fully characterized. RRBP1 has beenexcluded as a candidate gene in the cause of Alagille syndrome.Alternate splicing results in multiple transcript variants.
Ueno, T., et al. J. Biol. Chem. 285(39):29941-29950(2010)Ueno, T., et al. Exp. Cell Res. 316(3):329-340(2010)Krasnov, G.S., et al. Mol. Biol. (Mosk.) 43(2):348-356(2009)Benyamini, P., et al. Mol. Biol. Cell 20(2):732-744(2009)Bai, J.Z., et al. Cell Biol. Int. 32(5):473-483(2008)
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