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HOXA1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P49639
Clone Names 91013121
Peptide ID 91013121
Additional Information
Gene ID 3198
Other Names Homeobox protein Hox-A1, Homeobox protein Hox-1F, HOXA1, HOX1F
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXA1
Synonyms HOX1F
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

In vertebrates, the genes encoding the class oftranscription factors called homeobox genes are found in clustersnamed A, B, C, and D on four separate chromosomes. Expression ofthese proteins is spatially and temporally regulated duringembryonic development. This gene is part of the A cluster onchromosome 7 and encodes a DNA-binding transcription factor whichmay regulate gene expression, morphogenesis, and differentiation.The encoded protein may be involved in the placement of hindbrainsegments in the proper location along the anterior-posterior axisduring development. Two transcript variants encoding two differentisoforms have been found for this gene, with only one of theisoforms containing the homeodomain region.

References

Rankin, J.K., et al. J AAPOS 14(1):78-80(2010)Muscarella, L.A., et al. Mol Autism 1 (1), 9 (2010) :Canu, E., et al. J Neuroimaging 19(4):353-358(2009)Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)

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$ 80.00
Cat# BP18470a
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