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CD1B Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P29016
Clone Names 100427215
Peptide ID 100427215
Additional Information
Gene ID 910
Other Names T-cell surface glycoprotein CD1b, CD1b, CD1B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD1B
Function Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts
Tissue Location Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues
Research Areas
Citations (0)

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This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to late endosomes and lysosomes via atyrosine-based motif in the cytoplasmic tail, and requiresvesicular acidification to bind lipid antigens. [provided byRefSeq].


Davila, S., et al. Genes Immun. 11(3):232-238(2010)Felio, K., et al. J. Exp. Med. 206(11):2497-2509(2009)Guiard, J., et al. J. Immunol. 182(11):7030-7037(2009)Cui, Y., et al. Biol. Direct 4, 47 (2009) :Zajonc, D.M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(46):17925-17930(2008)

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$ 80.00
Cat# BP18475a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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